Narendran, Aru

Paediatric Oncology

Professor

MD, PhD

Web Presence:

Narendran Lab

Biography

Dr. Narendran has undergraduate and graduate degrees in Biochemistry and Immunology respectively, PhD in Neuroimmunology and a postdoctoral fellowship training in cancer biology from the Ontario Cancer Institute (OCI). His medical training was from McMaster University (MD), Tufts University, Massachusetts (Pediatrics Residency) and the Hospital for Sick Children, Toronto (Pediatric Hematology and Oncology fellowship). He is the recipient of a number of awards including the Odile Schweisguth International Prize for pediatric oncology research and the young investigator award from the Children’s oncology group (COG). Dr. Narendran is currently a professor of oncology and pediatrics. His current responsibilities also include directing a laboratory for preclinical and drug discovery studies and phase I clinical trials for children with currently incurable malignancies, training students and postdoctoral fellows in pediatric cancer research and teaching graduate level courses in cancer biology, novel cancer therapeutics and ethics in research. Dr. Narendran sits on the Research and Ethics Board (REB) for the Calgary Health Region.

Area of Focus

  • New therapies for refractory paediatric cancers

Summary of Research

Dr. Narendran’s laboratory focuses on the development of a “trial-in-a-cell” approach for future personalized cancer treatment in children. They have expertise in establishing molecularly relevant cell lines and tumor xenografts to screen libraries of novel therapeutics and biological agents for relapsed pediatric cancers. They are also establishing collaborations to derive genomic, epigenomic and transcriptomic data to find driver mutations and decisive genetic alterations in individual tumor specimens so druggable targets can be identified and matched to most applicable therapeutic agents for precision medicine in pediatric oncology. http://poeticphase1.org/biology/Preclinical.aspx

For career opportunities currently available in Dr. Narendran’s lab:  The Narendran Laboratory | Home (ucalgary.ca)
or forward enquiries to Michael O’Connell, E-mail: mwoconne@ucalgary.ca 

Area Of Focus

  • New therapies for refractory paediatric cancers

Summary Of Research

Dr. Narendran’s laboratory focuses on the development of a “trial-in-a-cell” approach for future personalized cancer treatment in children. They have expertise in establishing molecularly relevant cell lines and tumor xenografts to screen libraries of novel therapeutics and biological agents for relapsed pediatric cancers. They are also establishing collaborations to derive genomic, epigenomic and transcriptomic data to find driver mutations and decisive genetic alterations in individual tumor specimens so druggable targets can be identified and matched to most applicable therapeutic agents for precision medicine in pediatric oncology. http://poeticphase1.org/biology/Preclinical.aspx

For career opportunities currently available in Dr. Narendran’s lab:  The Narendran Laboratory | Home (ucalgary.ca)
or forward enquiries to Michael O’Connell, E-mail: mwoconne@ucalgary.ca